Pharmacokinetic Evaluation of Two Controlled Release Formulations of Nifedipine: GITS (Adalat Oros®) and Rhotard (Hadipine®)

Nifedipine GITS Package Insert

Invitro Release Comparison of Nifedipine from Marketed and Prepared Controlled Release Formulations by Mathematical Modeling

The objectives of this study were (a) To Perform in-vitro release study of marketed Nifedipine formulation,(b) To check effect of integrity on release profiles, (c) To determine the possibility of switchover from one formulation to another formulation and (d) To compare release profiles with formulated batches by application of mathematical models. Four marketed and two prepared controlled rele...

Evaluation of controlled-release mosquito repellent formulations.

Eight polymer and 9 microcapsule formulations of deet were tested on laboratory rabbits against Aedes aegypti and Anopheles albimanus. Several formulations were significantly more effective than simple (unformulated) deet at the same strength for periods up to 24 h. Best results were obtained with a polymer formulation containing a high molecular weight fatty acid and 3 microcapsule formulation...

Pharmacokinetic comparison of two valproic acid formulations--a plain and a controlled release enteric-coated tablets.

We investigated the single- and multiple dose pharmacokinetics of a new controlled-release formulation (Orfil retard enteric coated tablet) of valproic acid in comparison with those of the plain tablet as a reference. Twelve healthy volunteers were given each formulation of 300 mg in the single-dose study. In the steady-state multiple-dose study, twelve epileptic patients received 1200 mg/day o...

a comparative analysis of the marginal microleakages of two pit and fissure sealans, conseal-f and conseal clear

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